Journal Article

Regional Occurrence of Plasmid-Mediated SHV-7, an Extended-Spectrum β-Lactamase, in <i>Enterobacter cloacae</i> in Philadelphia Teaching Hospitals

Matthew E. Levison, Yamini V. Mailapur, Sandeep K. Pradhan, George A. Jacoby, Pamela Adams, Christopher L. Emery, Phyllis L. May and Peter G. Pitsakis

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 35, issue 12, pages 1551-1554
Published in print December 2002 | ISSN: 1058-4838
Published online December 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/344178
Regional Occurrence of Plasmid-Mediated SHV-7, an Extended-Spectrum β-Lactamase, in Enterobacter cloacae in Philadelphia Teaching Hospitals

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Although the production of extended-spectrum β-lactamases (ESBLs) by Klebsiella pneumoniae and Escherichia coli is an emerging problem, limited data are available regarding the frequency of ESBL production in other organisms. We provide the only description of regional occurrence of SHV-7 in Enterobacteriaceae other than E. coli or K. pneumoniae in the United States, and we emphasize that, among Enterobacter cloacae strains, not all resistance to extended-spectrum cephalosporins is the result of hyperproduction of AmpC β-lactamase.

Journal Article.  2328 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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