Journal Article

Borderline Tuberculoid Leprosy: An Immune Reconstitution Phenomenon in a Human Immunodeficiency Virus–Infected Person

S. D. Lawn, C. Wood and D. N. Lockwood

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 36, issue 1, pages e5-e6
Published in print January 2003 | ISSN: 1058-4838
Published online January 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/344446
Borderline Tuberculoid Leprosy: An Immune Reconstitution Phenomenon in a Human Immunodeficiency Virus–Infected Person

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Two months after starting highly active antiretroviral treatment (HAART), an individual with human immunodeficiency virus type 1 (HIV-1) infection and profound CD4+ T lymphocytopenia developed several erythematous plaques on his face, which were due to borderline tuberculoid leprosy with reversal reaction. The temporal association between the development of these lesions and changes in blood CD4+ lymphocyte count and plasma HIV-1 load observed during HAART strongly suggests that the presentation of leprosy resulted from immune reconstitution.

Journal Article.  1286 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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