Journal Article

The Effect of Race/Ethnicity on the Outcome of Highly Active Antiretroviral Therapy for Human Immunodeficiency Virus Type 1-Infected Patients

Søren Jensen-Fangel, Lars Pedersen, Court Pedersen, Carsten Schade Larsen, Palle Tauris, Axel Møller, Henrik Toft Sørensen and Niels Obel

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 35, issue 12, pages 1541-1548
Published in print December 2002 | ISSN: 1058-4838
Published online December 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/344769
The Effect of Race/Ethnicity on the Outcome of Highly Active Antiretroviral Therapy for Human Immunodeficiency Virus Type 1-Infected Patients

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We performed a population-based cohort study to assess the impact of nonwhite origin on the outcome of highly active antiretroviral therapy (HAART) for a Danish cohort of human immunodeficiency virus (HIV)-infected patients. A total of 389 whites and 135 nonwhites started receiving HAART before 1 April 2001. After 1 year of treatment, 78% of nonwhites and 76% of whites achieved a virus load of <500 HIV RNA copies/mL. No major differences were found between the 2 groups with respect to achievement of a virus load of <500 copies/mL (relative risk [RR], 0.94; 95% confidence interval [CI], 0.74–1.18), risk of clinical progression (RR, 0.63; 95% CI, 0.32–1.24), or response measured by total CD4+ cell count. One year after fulfilling Danish recommendations for initiation of HAART, 91% of nonwhites and 93% of whites had started receiving HAART. Race and ethnic origin play no major role in the outcome associated with HAART if access to health care is free.

Journal Article.  4616 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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