Journal Article

<i>Helicobacter</i> Species Ribosomal DNA Recovered from the Liver Tissue of Chinese Patients with Primary Hepatocellular Carcinoma

Xue-Gong Fan, Xiao-Ning Peng, Yan Huang, Javed Yakoob, Zhi-Ming Wang and Yong-Ping Chen

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 35, issue 12, pages 1555-1557
Published in print December 2002 | ISSN: 1058-4838
Published online December 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/344770
Helicobacter Species Ribosomal DNA Recovered from the Liver Tissue of Chinese Patients with Primary Hepatocellular Carcinoma

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Using polymerase chain reaction (PCR), we examined 16S ribosomal DNA (rDNA) of Helicobacter species in liver tissue specimens obtained from 15 patients with hepatocellular carcinoma. Sixty percent (9 of 15) of these specimens were found to be positive for Helicobacter species. Four 16S rDNA fragments from positive PCR samples were directly sequenced. By sequence comparison, all were found to be 99% identical to the 16S rRNA of Helicobacter pylori.

Journal Article.  1288 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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