Journal Article

Outcome of Penicillin-Susceptible Streptococcal Prosthetic Joint Infection Treated with Debridement and Retention of the Prosthesis

A. M. Meehan, D. R. Osmon, M. C. T. Duffy, A. D. Hanssen and M. R. Keating

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 36, issue 7, pages 845-849
Published in print April 2003 | ISSN: 1058-4838
Published online April 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/368182
Outcome of Penicillin-Susceptible Streptococcal Prosthetic Joint Infection Treated with Debridement and Retention of the Prosthesis

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Debridement with retention of the prosthesis was the initial treatment modality for 19 cases of penicillinsusceptible streptococcal prosthetic joint infection that occurred in 18 patients who presented to the Mayo Clinic (Rochester, Minnesota) during 1969–1998. All of the cases of prosthetic joint infection occurred <30 days after implantation of the prosthesis, which was well fixed at the time of debridement. The median duration of symptoms before debridement was 4 days (range, 1–10 days). Treatment failure (defined as relapse of infection with the original microorganism) occurred in 2 cases (10.5%) during a median follow-up period of 3.9 years (range, 0.3–21.7 years). The 1-year cumulative risk of relapse was 11% (95% confidence interval, 0%–26%). Relapse of prosthetic joint infection due to penicillin-susceptible streptococci after debridement and retention of the prosthesis is uncommon. For patients who present with a well-fixed prosthesis and a short duration of symptoms, debridement with retention appears to be an effective treatment modality.

Journal Article.  2965 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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