Journal Article

Extensive Retinal Neovascularization as a Late Finding in Human Immunodeficiency Virus-Infected Patients with Immune Recovery Uveitis

Mary E. Wright, Daniel L. Suzman, Karl G. Csaky, Henry Masur, Michael A. Polis and Michael R. Robinson

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 36, issue 8, pages 1063-1066
Published in print April 2003 | ISSN: 1058-4838
Published online April 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/374050
Extensive Retinal Neovascularization as a Late Finding in Human Immunodeficiency Virus-Infected Patients with Immune Recovery Uveitis

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Sixteen human immunodeficiency virus (HIV)-infected patients with inactive cytomegalovirus (CMV) retinitis who had discontinued systemic anti-CMV therapy while receiving highly active antiretroviral therapy (HAART) were prospectively observed. Fifteen patients developed immune recovery uveitis (IRU); 3 of the patients developed extensive retinal neovascularization, 1 of whom required vitrectomy for recurrent vitreous hemorrhages. These late complications indicate a need for continued ophthalmologic follow-up of HIV-infected patients who have a history of CMV retinitis, even for individuals who have not required anti-CMV therapy for >4 years.

Journal Article.  2060 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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