Journal Article

Improvement of Symptomatic Human Immunodeficiency Virus-Related Lymphoid Interstitial Pneumonia in Patients Receiving Highly Active Antiretroviral Therapy

Véronique Dufour, Marie Wislez, Emmanuel Bergot, Charles Mayaud and Jacques Cadranel

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 36, issue 10, pages e127-e130
Published in print May 2003 | ISSN: 1058-4838
Published online May 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/374665
Improvement of Symptomatic Human Immunodeficiency Virus-Related Lymphoid Interstitial Pneumonia in Patients Receiving Highly Active Antiretroviral Therapy

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To analyze the impact of highly active antiretroviral therapy on lymphoid interstitial pneumonia (LIP), we reviewed the medical files of 5 human immunodeficiency virus (HIV)-infected patients in whom LIP was diagnosed during 1996–2001 who had never previously received antiretroviral treatment. Patients were mildly immunosuppressed at the time of diagnosis of LIP but had high plasma HIV loads and marked circulating and pulmonary CD8 hyperlymphocytosis. All patients improved clinically, radiologically, and functionally; improvement was accompanied by a drastic reduction in the virus load and an increase in the CD4 lymphocyte count.

Journal Article.  2480 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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