Journal Article

Prolonged Perilesional Edema after Treatment of Parenchymal Neurocysticercosis: Methotrexate as a Corticosteroid-Sparing Agent

Paul B. Keiser and Theodore E. Nash

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 36, issue 10, pages e122-e126
Published in print May 2003 | ISSN: 1058-4838
Published online May 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/374667
Prolonged Perilesional Edema after Treatment of Parenchymal Neurocysticercosis: Methotrexate as a Corticosteroid-Sparing Agent

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Treatment of neurocysticercosis with larvicidal agents is commonly complicated by seizures and transient neurologic deficits as a result of the host immune response to dying cysts. We report a case in which treatment with high-dose praziquantel resulted in prolonged perilesional edema requiring use of corticosteroids and corticosteroid-sparing agents for >1 year, suggesting a role for methotrexate in the management of this condition.

Journal Article.  2128 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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