Journal Article

Topical Microbicides for Disease Prevention: Status and Challenges

Kenneth H. Meyer, Polly F. Harrison, Zeda Rosenberg and Jana Bowcut

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 36, issue 10, pages 1290-1294
Published in print May 2003 | ISSN: 1058-4838
Published online May 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/374834
Topical Microbicides for Disease Prevention: Status and Challenges

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As the human immunodeficiency virus and sexually transmitted disease epidemics advance relentlessly, it is clear that an armamentarium of therapeutic and preventive methods will be essential to their containment. Topical microbicides—self-administered prophylactic agents applied to the vagina or rectum in various formulations—could be a crucial addition to that necessary armamentarium. This article provides an update on the dramatically broadening array of approaches being pursued in microbicide research and development and identifies critical challenges to progress.

Journal Article.  2813 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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