Journal Article

Association of Hepatitis C Infection and Antiretroviral Use with Diabetes Mellitus in Drug Users

Andrea A. Howard, Robert S. Klein and Ellie E. Schoenbaum

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 36, issue 10, pages 1318-1323
Published in print May 2003 | ISSN: 1058-4838
Published online May 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/374838
Association of Hepatitis C Infection and Antiretroviral Use with Diabetes Mellitus in Drug Users

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We performed a cross-sectional analysis of factors associated with diabetes mellitus among 557 drug users who were recruited from a methadone treatment program and were participating in a longitudinal study of hepatitis C virus (HCV) infection. We found that HCV infection was strongly associated with diabetes mellitus (adjusted odds ratio [OR], 2.9; 95% confidence interval [CI], 1.3–6.4) after controlling for age, race, unemployment, and body mass index. Among HIV-infected drug users, receipt of antiretroviral therapy (ART) for >1 year was also associated with diabetes (adjusted OR for receipt of ART without a protease inhibitor, 4.1 [95% CI, 1.1–15.5]; adjusted OR for receipt of ART including a protease inhibitor, 5.5 [95% CI, 1.5–20.4]).

Journal Article.  2809 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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