Journal Article

Prevalence and Characteristics of Hepatitis C Virus Coinfection in a Human Immunodeficiency Virus Clinical Trials Group: The Terry Beirn Community Programs for Clinical Research on AIDS

Ellen M. Tedaldi, Katherine Huppler Hullsiek, Carlos D. Malvestutto, Roberto C. Arduino, Evelyn J. Fisher, Paul J. Gaglio, Elizabeth R. Jenny-Avital, Joseph P. McGowan and George Perez

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 36, issue 10, pages 1313-1317
Published in print May 2003 | ISSN: 1058-4838
Published online May 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/374841
Prevalence and Characteristics of Hepatitis C Virus Coinfection in a Human Immunodeficiency Virus Clinical Trials Group: The Terry Beirn Community Programs for Clinical Research on AIDS

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The baseline prevalence of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) coinfection among 2705 patients enrolled in HIV clinical trials in the Community Programs for Clinical Research on AIDS (CPCRA) was 16.6%. For men, multivariate logistic regression showed that the baseline prevalence of HIV-HCV coinfection was positively associated with history of injection drug use, older age, antiretroviral therapy naive status, African American or Latino ethnicity, and no history of having sex with men. No association was found with baseline CD4+ cell count or HIV RNA level. The prevalence of HCV coinfection in a diverse HIV clinical trials cohort provides additional information about risk behaviors and demographic factors that can be used in the analysis of clinical and virologic outcomes.

Journal Article.  2516 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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