Journal Article

The Use of Economic Modeling to Determine the Hospital Costs Associated with Nosocomial Infections

Rebecca R. Roberts, R. Douglas Scott, Ralph Cordell, Steven L. Solomon, Lynn Steele, Linda M. Kampe, William E. Trick and Robert A. Weinstein

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 36, issue 11, pages 1424-1432
Published in print June 2003 | ISSN: 1058-4838
Published online June 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/375061
The Use of Economic Modeling to Determine the Hospital Costs Associated with Nosocomial Infections

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Hospital-associated infection is well recognized as a patient safety concern requiring preventive interventions. However, hospitals are closely monitoring expenditures and need accurate estimates of potential cost savings from such prevention programs. We used a retrospective cohort design and economic modeling to determine the excess cost from the hospital perspective for hospital-associated infection in a random sample of adult medical patients. Study patients were classified as being not infected (n = 139), having suspected infection (n = 8), or having confirmed infection (n = 17). Severity of illness and intensive unit care use were both independently associated with increased cost. After controlling for these confounding effects, we found an excess cost of $6767 for suspected infection and $15,275 for confirmed hospital-acquired infection. The economic model explained 56% of the total variability in cost among patients. Hospitals can use these data when evaluating potential cost savings from effective infection-control measures.

Journal Article.  6207 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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