Journal Article

Vancomycin-Intermediate <i>Staphylococcus aureus</i> with Phenotypic Susceptibility to Methicillin in a Patient with Recurrent Bacteremia

Timothy S. Naimi, Daniel Anderson, Carol O'Boyle, David J. Boxrud, Susan K. Johnson, Fred C. Tenover and Ruth Lynfield

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 36, issue 12, pages 1609-1612
Published in print June 2003 | ISSN: 1058-4838
Published online June 2003 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/375228
Vancomycin-Intermediate Staphylococcus aureus with Phenotypic Susceptibility to Methicillin in a Patient with Recurrent Bacteremia

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Vancomycin-intermediate Staphylococcus aureus (VISA) are an emerging problem. We observed a statistically significant inverse relationship in the MICs of vancomycin and oxacillin in S. aureus isolates from a patient undergoing hemodialysis who received 26 weeks of treatment with vancomycin during November 1999 through April 2000. All isolates were mecA positive and were indistinguishable by pulsed-field gel electrophoresis. The evolving susceptibility patterns of this strain highlight the challenges of detecting and treating VISA infections.

Journal Article.  2557 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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