Journal Article

Pseudoneoplastic Appearance of Cytomegalovirus-Associated Colitis in Nonimmunocompromised Patients: Report of 2 Cases

Antonio Maiorana, Pietro Torricelli, Federica Giusti and Nicola Bellini

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 37, issue 5, pages e68-e71
Published in print September 2003 | ISSN: 1058-4838
Published online September 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/375876
Pseudoneoplastic Appearance of Cytomegalovirus-Associated Colitis in Nonimmunocompromised Patients: Report of 2 Cases

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Two cases of human cytomegalovirus (HCMV) colitis with pseudoneoplastic appearance are described. Patients presented with abdominal pain, fever, and diarrhea. Colonoscopy revealed a stenosing lesion in one patient and a broad-based, vegetant mass in the other patient, and histopathological examination of colectomy specimens revealed exuberant inflammatory masses with infiltration of mononuclear cells and ulcers with granulation tissue. Typical intranuclear HCMV inclusions were numerous. Peculiar to both patients was the lack of any apparent causes of immunodeficiency, such as human immunodeficiency virus infection or previous organ transplantation.

Journal Article.  2027 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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