Journal Article

<i>Aeromonas</i> Infection of the Hepatobiliary System: Report of 15 Cases and Review of the Literature

Nina M. Clark and Carol E. Chenoweth

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 37, issue 4, pages 506-513
Published in print August 2003 | ISSN: 1058-4838
Published online August 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/376629
Aeromonas Infection of the Hepatobiliary System: Report of 15 Cases and Review of the Literature

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Aeromonas species cause both intestinal and extraintestinal disease. We reviewed hospital laboratory and medical records to identify patients with Aeromonas infection of the hepatobiliary or pancreatic system. Analysis of data from our hospital, as well as a review of the published literature, yielded a total of 41 episodes in 39 patients, and the features of these episodes are described. The most common manifestation of Aeromonas hepatobiliary infection among all reported cases was cholangitis (29 of 41 episodes). The majority of infections in our hospital occurred in patients with underlying immunosuppression or malignancy (13 of 15 patients), including 4 liver transplant recipients, and nosocomial infection was not infrequent (8 of 17 episodes). Infection occurred most commonly in patients with obstruction of the biliary tract due to stones, tumor, or stricture and was associated with a relatively high mortality rate (11.8%). Antibiotic susceptibility testing revealed that gentamicin, imipenem, and ciprofloxacin had the highest activity against the Aeromonas species isolated.

Journal Article.  4451 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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