Journal Article

Recurring Thrombocytopenia Associated with Structured Treatment Interruption in Patients with Human Immunodeficiency Virus Infection

Jintanat Ananworanich, Nittaya Phanuphak, Reto Nuesch, Wichitra Apateerapong, Ponlapat Rojnuckarin, Sasiwimol Ubolyam, Praphan Phanuphak and Kiat Ruxrungtham

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 37, issue 5, pages 723-725
Published in print September 2003 | ISSN: 1058-4838
Published online September 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/376989
Recurring Thrombocytopenia Associated with Structured Treatment Interruption in Patients with Human Immunodeficiency Virus Infection

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In a structured treatment interruption (STI) trial, 3 of 23 patients in a CD4 cell count-guided treatment arm developed recurring thrombocytopenia associated with the interruption of antiretroviral therapy. All 3 patients had slightly low or normal platelet counts before initiating antiretroviral therapy. STI may play a role in inducing thrombocytopenia in patients with human immunodeficiency virus infection.

Journal Article.  1705 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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