Journal Article

Shunt Surgery for Hydrocephalus Complicating Cryptococcal Meningitis in Human Immunodeficiency Virus-Negative Patients

Po-Chou Liliang, Cheng-Loong Liang, Wen-Neng Chang, Han-Jung Chen, Thung-Ming Su, Kang Lu and Cheng-Hsien Lu

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 37, issue 5, pages 673-678
Published in print September 2003 | ISSN: 1058-4838
Published online September 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/377208
Shunt Surgery for Hydrocephalus Complicating Cryptococcal Meningitis in Human Immunodeficiency Virus-Negative Patients

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From 1988 through 2001, 27 patients with cryptococcal meningitis who had hydrocephalus were identified and were treated by placement of ventriculoperitoneal (VP) shunts. To assess the predictive value of the response to VP shunts in terms of outcome in these patients, univariate analysis for variables was performed. Poor outcome was associated with a Glasgow Coma Scale score of ⩽8 (P < .001) and duration of altered consciousness of >48 h (P = .02). Use of VP shunts did not result in a good response or outcome in comatose patients. Thus, any delay in the diagnosis or treatment of patients with hydrocephalus could cause a deterioration of consciousness and is associated with poor outcome.

Journal Article.  2735 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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