Journal Article

Serum Concentrations of Pneumococcal Anticapsular Antibodies in Children with Pneumonia Associated with <i>Streptococcus pneumonia</i> Infection

Susanna Esposito, Roberta Droghetti, Nadia Faelli, Annalisa Lastrico, Claudia Tagliabue, Laura Cesati, Ciro Bianchi and Nicola Principi

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 37, issue 9, pages 1261-1264
Published in print November 2003 | ISSN: 1058-4838
Published online November 2003 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/378740
Serum Concentrations of Pneumococcal Anticapsular Antibodies in Children with Pneumonia Associated with Streptococcus pneumonia Infection

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The levels of specific IgG antibody to pneumococcal capsular polysaccharides were investigated in 182 children, aged 2–5 years, who were hospitalized for community-acquired pneumonia, including 55 (30.2%) with evidence of acute pneumococcal infection. Results show that children with concentrations of specific IgG antibody that would protect against invasive disease do not seem to be protected against pneumonia associated with pneumococcal infection.

Journal Article.  2560 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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