Journal Article

Adverse Reactions to Accidental Forearm Injection of Bacille Calmette-Guérin Vaccine in Schoolchildren: 12-Month Cohort Follow-up

Samuel Gross, Ernesto Kahan, Liora Vesterman, Ofra Havkin and Alex Leventhal

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 38, issue 10, pages 1495-1497
Published in print May 2004 | ISSN: 1058-4838
Published online May 2004 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/392505
Adverse Reactions to Accidental Forearm Injection of Bacille Calmette-Guérin Vaccine in Schoolchildren: 12-Month Cohort Follow-up

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This study examined the natural history of reaction after accidental intradermal administration of bacille Calmette-Guérin (BCG) vaccine instead of purified protein derivative (PPD) in 226 schoolchildren. At 18 days after vaccination, a local reaction with a diameter of 4.5–14 mm was found in 62% of the students, and ulceration with discharge was found in 26.6%; corresponding rates at 120 days were 72.3% and 38% and at 281 days were 73% and 6%. At 345 days, 85% of the students had a dry scar measuring 5–14 mm in diameter, and none had ulceration or discharge.

Journal Article.  2044 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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