Journal Article

The Use and Interpretation of Quasi-Experimental Studies in Infectious Diseases

George M. Eliopoulos, Anthony D. Harris, Douglas D. Bradham, Mona Baumgarten, Ilene H. Zuckerman, Jeffrey C. Fink and Eli N. Perencevich

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 38, issue 11, pages 1586-1591
Published in print June 2004 | ISSN: 1058-4838
Published online June 2004 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/420936
The Use and Interpretation of Quasi-Experimental Studies in Infectious Diseases

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  • Infectious Diseases
  • Immunology
  • Public Health and Epidemiology
  • Microbiology

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Quasi-experimental study designs, sometimes called nonrandomized, pre-post-intervention study designs, are ubiquitous in the infectious diseases literature, particularly in the area of interventions aimed at decreasing the spread of antibiotic-resistant bacteria. Little has been written about the benefits and limitations of the quasi-experimental approach. This article outlines a hierarchy of quasi-experimental study design that is applicable to infectious diseases studies and that, if applied, may lead to sounder research and more-convincing causal links between infectious diseases interventions and outcomes.

Journal Article.  3566 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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