Journal Article

Breakthrough Fungal Infections in Stem Cell Transplant Recipients Receiving Voriconazole

Alexander Imhof, S. Arunmozhi Balajee, David N. Fredricks, Janet A. Englund and Kieren A. Marr

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 39, issue 5, pages 743-746
Published in print September 2004 | ISSN: 1058-4838
Published online September 2004 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/423274
Breakthrough Fungal Infections in Stem Cell Transplant Recipients Receiving Voriconazole

More Like This

Show all results sharing these subjects:

  • Infectious Diseases
  • Immunology
  • Public Health and Epidemiology
  • Microbiology

GO

Show Summary Details

Preview

Infection with voriconazole-resistant fungi may become problematic, because organisms with decreased susceptibility have been noted. Breakthrough fungal infections occurred in 13 of 139 patients who received voriconazole at our center during the period of September 1998 through September 2003. Zygomycetes were found in 6 patients, and Candida glabrata bloodstream infection occurred in 4 patients. Minimal inhibitory concentrations were ⩾1 µg/mL for all available isolates. Yeasts and molds with decreased susceptibility to voriconazole may cause invasive infection in patients treated successfully for aspergillosis.

Journal Article.  2272 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.