Journal Article

Factors Associated with Psychosis among Patients with Severe Acute Respiratory Syndrome: A Case-Control Study

Dominic T. S. Lee, Y. K. Wing, Henry C. M. Leung, Joseph J. Y. Sung, Y. K. Ng, G. C. Yiu, Ronald Y. L. Chen and Helen F. K. Chiu

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 39, issue 8, pages 1247-1249
Published in print October 2004 | ISSN: 1058-4838
Published online October 2004 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/424016
Factors Associated with Psychosis among Patients with Severe Acute Respiratory Syndrome: A Case-Control Study

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We observed that a number of patients with severe acute respiratory syndrome (SARS) developed affective psychosis during the acute phase of their illness. We reviewed all SARS-related psychiatric consultations in Hong Kong and investigated the risk factors for psychosis among patients with SARS in a matched case-control study. Patients with SARS-related psychosis received higher total doses of steroids and had higher rates of family history of psychiatric illness. The findings of the present study suggest that steroid toxicity, personal vulnerability, and, probably, psychosocial stressors jointly contributed to the development of psychosis in patients with SARS.

Journal Article.  1844 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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