Journal Article

Mass Antibiotic Treatment and Community Protection in Trachoma Control Programs

Jaya D. Chidambaram, Muluken Melese, Wondu Alemayehu, Elizabeth Yi, Tisha Prabriputaloong, David C. Lee, Vicky Cevallos, Zhaoxia Zhou, John P. Whitcher, Bruce D. Gaynor and Thomas M. Lietman

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 39, issue 9, pages e95-e97
Published in print November 2004 | ISSN: 1058-4838
Published online November 2004 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/424747
Mass Antibiotic Treatment and Community Protection in Trachoma Control Programs

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Azithromycin is highly effective against trachoma, but the practical difficulties of community-wide distribution often leave many individuals untreated. We demonstrate, after mass azithromycin treatment of a population in Ethiopia, an indirect protective effect that occurred among untreated children who resided in villages in which most individuals had been treated. Similarities with the indirect protection within a treated community (i.e., “herd protection”) that has been observed in vaccination programs are discussed.

Journal Article.  2078 words. 

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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