Journal Article

Trends in AIDS-Defining and Non—AIDS-Defining Malignancies among HIV-Infected Patients: 1989–2002

Roger Bedimo, Ray Y. Chen, Neil A. Accortt, James L. Raper, Carol Linn, Jeroan J. Allison, John Dubay, Michael S. Saag and Craig J. Hoesley

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 39, issue 9, pages 1380-1384
Published in print November 2004 | ISSN: 1058-4838
Published online November 2004 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/424883
Trends in AIDS-Defining and Non—AIDS-Defining Malignancies among HIV-Infected Patients: 1989–2002

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In a comparison of rates of acquired immunodeficiency syndrome (AIDS)–defining malignancies (ADMs) for 1989–1996 versus 1997–2002, we found a decrease in ADMs (rate ratio, 0.31; P < .0001) and a significant increase in non—AIDS-defining malignancies (non-ADMs; rate ratio, 10.87; P < .0002). The mean CD4 cell count was lower among patients with ADMs than among those with non-ADMs. A longer duration of survival during highly active antiretroviral therapy might explain the increasing incidence of non-ADMs.

Journal Article.  2397 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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