Journal Article

Two Cases of Fatal Shock after Transfusion of Platelets Contaminated by <i>Staphylococcus aureus:</i> Role of Superantigenic Toxins

Thomas Perpoint, Gerard Lina, Claire Poyart, Bertille de Barbeyrac, Richard Traineau, Michel Jeanne, François Vandenesch and Jerome Etienne

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 39, issue 10, pages e106-e109
Published in print November 2004 | ISSN: 1058-4838
Published online November 2004 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/425499
Two Cases of Fatal Shock after Transfusion of Platelets Contaminated by Staphylococcus aureus: Role of Superantigenic Toxins

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We detected Staphylococcus aureus superantigenic toxins in the platelet infusion bags that had been used for 2 patients who subsequently developed transfusion-associated Staphylococcus aureus infection. Both patients, who were immunodeficient, developed manifestations of toxic shock syndrome and septic shock, and they died soon after the onset of infection.

Journal Article.  2150 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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