Journal Article

Successful Desensitization to Enfuvirtide after a Hypersensitivity Reaction in an HIV-1-Infected Man

Joseph A. DeSimone, Ambrish Ojha, Rolee Pathak and John Cohn

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 39, issue 10, pages e110-e112
Published in print November 2004 | ISSN: 1058-4838
Published online November 2004 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/425502
Successful Desensitization to Enfuvirtide after a Hypersensitivity Reaction in an HIV-1-Infected Man

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We report a case of successful, rapid desensitization to enfuvirtide after a hypersensitivity reaction in a man with highly drug-resistant human immunodeficiency virus type 1 infection. The patient was desensitized in a monitored intensive care unit and tolerated the rapid desensitization protocol without any serious adverse effects. This case illustrates the ability to safely desensitize patients with limited treatment options who require enfuvirtide therapy.

Journal Article.  1627 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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