Journal Article

Resistance to Dual Nucleoside Reverse-Transcriptase Inhibitors in Children Infected with HIV Clade A/E

Rangsima Lolekha, Sunee Sirivichayakul, Umaporn Siangphoe, Chitsanu Pancharoen, Suchada Kaewchana, Wichitra Apateerapong, Apicha Mahanontharit, Tawee Chotpitayasunondh, Kiat Ruxrungtham, Praphan Phanuphak and Jintanat Ananworanich

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 40, issue 2, pages 309-312
Published in print January 2005 | ISSN: 1058-4838
Published online January 2005 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/427026
Resistance to Dual Nucleoside Reverse-Transcriptase Inhibitors in Children Infected with HIV Clade A/E

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The prevalence of nucleoside reverse-transcriptase inhibitor (NRTI) mutations was determined among 95 human immunodeficiency virus—infected Thai children who were treated with dual nucleoside reverse-transcriptase inhibitors. Almost all children had resistance to at least 1 NRTI, and approximately half of the children had resistance to multiple NRTIs. Cross-resistance to stavudine and azidothymidine was universal.

Journal Article.  2445 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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