Journal Article

Prevalence of Mixed Cryoglobulins in Relation to CD4 Cell Count among Patients Coinfected with HIV and Hepatitis C Virus

Laurent Aaron, Pascal Lebray, Marie-Alexandra Alyanakian, Laurent Roudière, Audrey Therby, Marie-Laure Chaix, Bertrand Dupont, Stanislas Pol and Jean-Paul Viard

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 40, issue 2, pages 306-308
Published in print January 2005 | ISSN: 1058-4838
Published online January 2005 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/427029
Prevalence of Mixed Cryoglobulins in Relation to CD4 Cell Count among Patients Coinfected with HIV and Hepatitis C Virus

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Cryoglobulinemia was studied in human immunodeficiency virus—positive, hepatitis C virus (HCV)—positive patients in relation to their CD4 cell count. Cryoglobulinemia was found in 18 (31.6%) of 57 patients: 17 (44.7%) of 38 patients with a CD4 cell count of ⩾200 cells/µL versus 1 (5.3%) of 19 patients with a CD4 cell count of <200 cells/µL (P = .0064). Cell-mediated immunity could, therefore, contribute to the production of HCV-associated cryoglobulins.

Journal Article.  1926 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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