Journal Article

Serotype Distribution of Invasive Group B Streptococcal Isolates in Infants: Results from a Nationwide Active Laboratory Surveillance Study over 2 Years in Germany

Kirsten Fluegge, Sven Supper, Anette Siedler and Reinhard Berner

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 40, issue 5, pages 760-763
Published in print March 2005 | ISSN: 1058-4838
Published online March 2005 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/427942
Serotype Distribution of Invasive Group B Streptococcal Isolates in Infants: Results from a Nationwide Active Laboratory Surveillance Study over 2 Years in Germany

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We report the serotype distribution of invasive group B streptococci (GBS) isolated from 296 infants in Germany. Serotype distribution was as follows: serotype Ia, 15%; Ib, 5%; II, 5%; III, 65%; IV, 1%; and V, 8%. Analysis of serotype according to the source of isolation highlighted the considerable role of serotype III in meningitis in early-onset infection (82%) and late-onset infection (84%). Use of a trivalent GBS vaccine in Germany could theoretically provide protection against 84% and 94% of invasive early-onset and late-onset infections, respectively.

Journal Article.  2351 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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