Journal Article

Characterization and Management of Paradoxical Upgrading Reactions in HIV-Uninfected Patients with Lymph Node Tuberculosis

Charlotte R. Hawkey, Timothy Yap, Janis Pereira, David A. J. Moore, Robert N. Davidson, Geoffrey Pasvol, Onn Min Kon, Robert A. Wall and Robert J. Wilkinson

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 40, issue 9, pages 1368-1371
Published in print May 2005 | ISSN: 1058-4838
Published online May 2005 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/429317
Characterization and Management of Paradoxical Upgrading Reactions in HIV-Uninfected Patients with Lymph Node Tuberculosis

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In a retrospective analysis, paradoxical deterioration of lymph node tuberculosis in human immunodeficiency virus-uninfected patients was common, occurring in 25 (23%) of 109 patients after treatment had been given for a median of 46 days (interquartile range, 21–139 days) and persisting for a median of 67.5 days (interquartile range, 34–111 days). We found no association between the use of steroids and the duration of reaction.

Journal Article.  2172 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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