Journal Article

Quantification of Adenovirus in the Lower Respiratory Tract of Patients without Clinical Adenovirus-Related Respiratory Disease

Anskar Yu-Hung Leung, Maggie Chan, Vincent Chi-Chung Cheng, Kwok-Yung Yuen and Yok-Lam Kwong

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 40, issue 10, pages 1541-1544
Published in print May 2005 | ISSN: 1058-4838
Published online May 2005 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/429627
Quantification of Adenovirus in the Lower Respiratory Tract of Patients without Clinical Adenovirus-Related Respiratory Disease

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Adenovirus in bronchoalveolar lavage fluid samples from 50 patients without adenovirus-related illness was quantified. In 49 patients, adenovirus was found (median load, 3.3 × 103 copies/µg of DNA). The adenovirus load was inversely related to lymphocyte count (Pearson correlation coefficient r = −0.311; P = .03) and was significantly greater in immunosuppressed patients than in immunocompetent patients (5.1 × 103 vs. 2.0 × 103 copies/µg of DNA; P = .028).

Journal Article.  2121 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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