Journal Article

Discontinuation of Primary Prophylaxis against <i>Mycobacterium avium</i> Complex Infection in HIV-Infected Persons Receiving Antiretroviral Therapy: Observations from a Large National Cohort in the United States, 1992–2002

John T. Brooks, Ruiguang Song, Debra L. Hanson, Mitchell Wolfe and David L. Swerdlow

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 41, issue 4, pages 549-553
Published in print August 2005 | ISSN: 1058-4838
Published online August 2005 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/432057
Discontinuation of Primary Prophylaxis against Mycobacterium avium Complex Infection in HIV-Infected Persons Receiving Antiretroviral Therapy: Observations from a Large National Cohort in the United States, 1992–2002

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In a large, diverse cohort of human immunodeficiency virus (HIV)–infected persons receiving routine care, the proportion of eligible persons who discontinued primary prophylaxis against Mycobacterium avium complex (MAC) infection, according to guidelines of the US Public Health Service and the Infectious Diseases Society of America, increased from 16.7% (in 1996) to 84.9% (in 2002). The discontinuation of primary prophylaxis was not associated with an increased risk of disseminated MAC infection.

Journal Article.  2105 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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