Journal Article

Immune Reconstitution Syndrome Due to Bacillus Calmette-Guérin after Initiation of Antiretroviral Therapy in Children with HIV Infection

Thanyawee Puthanakit, Penninah Oberdorfer, Suchart Punjaisee, Pornphun Wannarit, Thira Sirisanthana and Virat Sirisanthana

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 41, issue 7, pages 1049-1052
Published in print October 2005 | ISSN: 1058-4838
Published online October 2005 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/433177
Immune Reconstitution Syndrome Due to Bacillus Calmette-Guérin after Initiation of Antiretroviral Therapy in Children with HIV Infection

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The immune reconstitution syndrome caused by bacillus Calmette-Guérin (BCG) was found in 4 HIV-infected children who were immunized with BCG at birth. The localized, suppurative, BCG-related complications developed within 10 weeks after initiation of antiretroviral therapy. The incidence rate was 2.7 cases per 100 persons (95% confidence interval, 0.7–6.7). Patients responded well to treatment with isoniazid and rifampicin.

Journal Article.  1750 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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