Journal Article

Long-Term Remission in Progressive Multifocal Leukoencephalopathy Caused by Idiopathic CD4<sup>+</sup> T Lymphocytopenia: A Case Report

M. A. Rueger, H. Miletic, K. Dorries, C. Wyen, C. Eggers, M. Deckert, G. Faetkenheuer and A. H. Jacobs

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 42, issue 7, pages e53-e56
Published in print April 2006 | ISSN: 1058-4838
Published online April 2006 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/500400
Long-Term Remission in Progressive Multifocal Leukoencephalopathy Caused by Idiopathic CD4+ T Lymphocytopenia: A Case Report

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Progressive multifocal leukoencephalopathy is caused by JC virus, an opportunistic infection of the central nervous system. Antiretroviral treatment for progressive multifocal leukoencephalopathy in human immunodeficiency virus—infected patients is beneficial, but few data exist for patients who are not infected with human immunodeficiency virus. Idiopathic CD4+ T lymphocytopenia excludes human immunodeficiency virus infection. We describe a patient with progressive multifocal leukoencephalopathy with underlying idiopathic CD4+ T lymphocytopenia in whom functional recovery occurred without antiviral therapy.

Journal Article.  2151 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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