Journal Article

Deep-Seated Resistance in Relapsed Paratyphoid Fever

Graham S. Cooke, Fiona J. Cooke, Madeline Stone, Keith Turner, Adil Al Nahhas, Zarni Win, John Wain, Thomas R. Rogers, Jon S. Friedland and Kathleen B. Bamford

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 42, issue 11, pages e92-e94
Published in print June 2006 | ISSN: 1058-4838
Published online June 2006 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/503562
Deep-Seated Resistance in Relapsed Paratyphoid Fever

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We describe a case of relapsed paratyphoid fever in which the isolate had reduced susceptibility to ciprofloxacin due to a rare mutation within the gyrA gene. 18Fluorodeoxyglucose positron emission tomography scanning identified deep-seated infection including unsuspected aortitis and highlights the utility of novel imaging techniques to improve our understanding and treatment of this disease.

Journal Article.  1339 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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