Journal Article

Pertussis Serostatus among Neonates Born to Hispanic Women

C. Mary Healy, Marcia A. Rench, Kathryn M. Edwards and Carol J. Baker

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 42, issue 10, pages 1439-1442
Published in print May 2006 | ISSN: 1058-4838
Published online May 2006 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/503567
Pertussis Serostatus among Neonates Born to Hispanic Women

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The reasons for the higher pertussis incidence among Hispanic infants, compared with among infants of other ethnicities, are unknown. The geometric mean concentration of pertussis toxin—specific immunoglobulin G in serum samples from 220 Hispanic neonates was 8.45 EU/mL, as determined by enzyme-linked immunosorbent assay, and it was significantly lower if mothers were adolescents (4.63 EU/mL; P ⩽ .001). A lack of maternal immunity is one explanation for pertussis susceptibility in very young Hispanic infants.

Journal Article.  2481 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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