Journal Article

HIV Type 1 RNA Level as a Clinical Indicator of Renal Pathology in HIV-Infected Patients

Michelle Estrella, Derek M. Fine, Joel E. Gallant, M. Hafizur Rahman, Nagapradeep Nagajothi, Lorraine C. Racusen, Paul J. Scheel and Mohamed G. Atta

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 43, issue 3, pages 377-380
Published in print August 2006 | ISSN: 1058-4838
Published online August 2006 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/505497
HIV Type 1 RNA Level as a Clinical Indicator of Renal Pathology in HIV-Infected Patients

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To determine the value of human immunodeficiency virus type 1 (HIV-1) RNA level in distinguishing HIV-associated nephropathy from non–HIV-associated nephropathy renal pathological conditions, we retrospectively compared renal histopathological findings for 86 HIV-infected patients according to HIV-1 RNA levels. We found that HIV-associated nephropathy was unlikely among patients with HIV-1 RNA levels <400 copies/mL. Hypertensive vascular disease surpassed HIV-associated nephropathy as the most common renal pathological finding among the entire cohort. HIV-1 RNA level did not correlate with renal survival.

Journal Article.  2292 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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