Journal Article

Paradoxical Increase in Circulating <i>Aspergillus</i> Antigen during Treatment with Caspofungin in a Patient with Pulmonary Aspergillosis

Rocus R. Klont, Monique A. S. H. Mennink-Kersten, Dorien Ruegebrink, Antonius J. M. M. Rijs, Nicole M. A. Blijlevens, J. Peter Donnelly and Paul E. Verweij

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 43, issue 3, pages e23-e25
Published in print August 2006 | ISSN: 1058-4838
Published online August 2006 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/505603
Paradoxical Increase in Circulating Aspergillus Antigen during Treatment with Caspofungin in a Patient with Pulmonary Aspergillosis

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A paradoxical increase in circulating Aspergillus antigen was observed during treatment with caspofungin in a patient with proven invasive aspergillosis. With the exception of treatment with the echinocandin, no other factors were found that might explain this clinical observation, which was supported by experiments done in vitro.

Journal Article.  2083 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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