Journal Article

<i>Cryptococcus gattii</i> Infection: Characteristics and Epidemiology of Cases Identified in a South African Province with High HIV Seroprevalence, 2002–2004

Juliette Morgan, Kerrigan M. McCarthy, Susan Gould, Ke Fan, Beth Arthington-Skaggs, Naureen Iqbal, Karen Stamey, Rana A. Hajjeh and Mary E. Brandt

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 43, issue 8, pages 1077-1080
Published in print October 2006 | ISSN: 1058-4838
Published online October 2006 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/507897
Cryptococcus gattii Infection: Characteristics and Epidemiology of Cases Identified in a South African Province with High HIV Seroprevalence, 2002–2004

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We describe 46 Cryptococcus gattii—infected persons identified by population-based surveillance conducted in South Africa. Most patients with C. gattii infection presented with meningitis. The mortality rate during hospitalization was 36%. We found no significant differences between persons with and persons without C. gattii infection with regard to clinical presentation, acquired immunodeficiency syndrome diagnosis, concomitant conditions, or prior opportunistic infections. C. gattii isolates had low MICs to the tested antifungal drugs.

Journal Article.  2636 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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