Journal Article

Assessment of the Utility of Viral Culture of Cerebrospinal Fluid

Christopher R. Polage and Cathy A. Petti

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 43, issue 12, pages 1578-1579
Published in print December 2006 | ISSN: 1058-4838
Published online December 2006 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/509581
Assessment of the Utility of Viral Culture of Cerebrospinal Fluid

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Nucleic acid amplification testing is the preferred method to detect enteroviruses and Herpesviridae in cerebrospinal fluid, but clinicians still request viral culture. Review of 22,394 viral cultures of cerebrospinal fluid samples found that <0.1% recovered nonenterovirus, non-Herpesviridae species, suggesting that, when nucleic acid amplification testing is performed, viral culture may have no additional benefit.

Journal Article.  1671 words. 

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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