Journal Article

Recommendations for the Management of Herpes Zoster

Robert H. Dworkin, Robert W. Johnson, Judith Breuer, John W. Gnann, Myron J. Levin, Miroslav Backonja, Robert F. Betts, Anne A. Gershon, Maija L. Haanpää, Michael W. McKendrick, Turo J. Nurmikko, Anne Louise Oaklander, Michael N. Oxman, Deborah Pavan Langston, Karin L. Petersen, Michael C. Rowbotham, Kenneth E. Schmader, Brett R. Stacey, Stephen K. Tyring, Albert J. M. van Wijck, Mark S. Wallace, Sawko W. Wassilew and Richard J. Whitley

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 44, issue Supplement_1, pages S1-S26
Published in print January 2007 | ISSN: 1058-4838
Published online January 2007 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/510206
Recommendations for the Management of Herpes Zoster

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The objective of this article is to provide evidence-based recommendations for the management of patients with herpes zoster (HZ) that take into account clinical efficacy, adverse effects, impact on quality of life, and costs of treatment. Systematic literature reviews, published randomized clinical trials, existing guidelines, and the authors' clinical and research experience relevant to the management of patients with HZ were reviewed at a consensus meeting. The results of controlled trials and the clinical experience of the authors support the use of acyclovir, brivudin (where available), famciclovir, and valacyclovir as first-line antiviral therapy for the treatment of patients with HZ. Specific recommendations for the use of these medications are provided. In addition, suggestions are made for treatments that, when used in combination with antiviral therapy, may further reduce pain and other complications of HZ.

Journal Article.  21096 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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