Journal Article

Interruption of Recurrent Clostridium difficile-Associated Diarrhea Episodes by Serial Therapy with Vancomycin and Rifaximin

Stuart Johnson, Christopher Schriever, Minerva Galang, Ciarán P. Kelly and Dale N. Gerding

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 44, issue 6, pages 846-848
Published in print March 2007 | ISSN: 1058-4838
Published online March 2007 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/511870
Interruption of Recurrent Clostridium difficile-Associated Diarrhea Episodes by Serial Therapy with Vancomycin and Rifaximin

More Like This

Show all results sharing these subjects:

  • Infectious Diseases
  • Immunology
  • Public Health and Epidemiology
  • Microbiology

GO

Show Summary Details

Preview

Eight women who each experienced 4–8 episodes of Clostridium difficile–associated diarrhea were given a 2-week course of rifaximin therapy when they were asymptomatic, immediately after completing their last course of vancomycin therapy. Seven of the 8 patients experienced no further diarrhea recurrence. The patient who had a recurrence responded to a second course of rifaximin therapy, but rifaximin-resistant C. difficile was recovered after treatment. A controlled trial for treating recurrent Clostridium difficile–associated diarrhea appears to be warranted.

Journal Article.  2104 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.