During a large pertussis outbreak, culture and polymerase chain reaction (PCR) were used to identify 149 case patients; of these case patients, 79 had positive PCR and culture results, 59 had positive PCR results and negative culture results, 11 had negative PCR results and positive culture results (10 PCR-negative, culture-positive specimens were collected ⩽14 days after illness onset). PCR and culture of samples obtained ⩽2 weeks after illness onset and PCR of samples obtained >2 weeks after illness onset proved to be most diagnostically useful.
Journal Article. 2197 words. Illustrated.
Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology
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