Journal Article

<i>Burkholderia pseudomallei</i> Infection in a Puerto Rican Patient with Chronic Granulomatous Disease: Case Report and Review of Occurrences in the Americas

Susan E. Dorman, Vee J. Gill, John I. Gallin and Steven M. Holland

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 26, issue 4, pages 889-894
Published in print April 1998 | ISSN: 1058-4838
Published online April 1998 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/513928
Burkholderia pseudomallei Infection in a Puerto Rican Patient with Chronic Granulomatous Disease: Case Report and Review of Occurrences in the Americas

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Burkholderia species, notably Burkholderia cepacia and Burkholderia gladioli, are important pathogens in patients with chronic granulomatous disease (CGD). Burkholderia pseudomallei, the causative agent of melioidosis, is endemic in Southeast Asia and northern Australia but is a rare pathogen in other parts of the world. We describe the occurrence of B. pseudomallei infection in a Puerto Rican patient with CGD. This is one of only a small number of documented cases of melioidosis autochthonous to the Americas and is the first reported case of B. pseudomallei infection in a CGD patient from the Americas. We conclude that B. pseudomallei, like B. cepacia and B. gladioli, should be considered a potential pathogen in patients with CGD and that melioidosis should be considered in the differential diagnosis for ill residents of or travelers to Puerto Rico.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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