Journal Article

Minocycline and Ethylenediaminetetraacetate for the Prevention of Recurrent Vascular Catheter Infections

Issam Raad, Antonio Buzaid, Janelle Rhyne, Ray Hachem, Rabih Darouiche, Hossam Safar, Maher Albitar and Robert J. Sherertz

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 25, issue 1, pages 149-151
Published in print July 1997 | ISSN: 1058-4838
Published online July 1997 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/514518
Minocycline and Ethylenediaminetetraacetate for the Prevention of Recurrent Vascular Catheter Infections

More Like This

Show all results sharing these subjects:

  • Infectious Diseases
  • Immunology
  • Public Health and Epidemiology
  • Microbiology

GO

Show Summary Details

Preview

Three patients with recurrent vascular catheter-related bacteremia were successfully treated by allowing a solution of minocycline and ethylenediaminetetraacetate (EDTA) to dwell in the lumen of the indwelling catheter or by coating polyurethane catheters with minocycline/EDTA and flushing the lumen daily with the same solution. In vitro and in vivo experiments showed that minocycline/ EDTA may have broad-spectrum antimicrobial activity, may have optimal anticoagulant activity, and may be highly efficacious in preventing catheter colonization.

Journal Article.  0 words. 

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.