Journal Article

Vertebral Osteomyelitis Due to <i>Rhodococcus equi</i> in a Liver Transplant Recipient

Lutz Fischer, Martina Sterneck, Helmut Albrecht, Gerrit Krupski, Susanne Polywka, Xavier Rogiers and Christoph E. Broelsch

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 26, issue 3, pages 749-752
Published in print March 1998 | ISSN: 1058-4838
Published online March 1998 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/514596
Vertebral Osteomyelitis Due to Rhodococcus equi in a Liver Transplant Recipient

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Rhodococcus equi is a rare but well-documented cause of cavitary pneumonia in immunocompromised patients. In this report the first case of R. equi infection manifesting as vertebral osteomyelitis is described. A 39-year-old liver transplant recipient presented with recurrent pneumonia and a pleura-based lung abscess and subsequently developed osteomyelitis of the lower thoracic spine. Surgical debridement and prolonged treatment with rifabutin and clarithromycin resulted in clinical cure. In the literature, 12 other cases of R. equi infection in solid-organ transplant recipients have been reported. Ten of these patients had documented pulmonary disease and seven had extrapulmonary manifestations. Prolonged antibiotic therapy and surgical drainage resulted in clinical improvement in >90% of the reported cases.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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