Journal Article

Streptomyces Pneumonia in a Patient with Human Immunodeficiency Virus Infection: Case Report and Review of the Literature on Invasive Streptomyces Infections

Eileen F. Dunne, William J. Burman and Michael L. Wilson

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 27, issue 1, pages 93-96
Published in print July 1998 | ISSN: 1058-4838
Published online July 1998 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/514612
Streptomyces Pneumonia in a Patient with Human Immunodeficiency Virus Infection: Case Report and Review of the Literature on Invasive Streptomyces Infections

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Streptomyces species are most widely known for their production of antimicrobial substances and, apart from mycetoma, have rarely been reported as a cause of infection. We describe a patient with early human immunodeficiency virus infection who presented with fever, cough, and nodular pulmonary infiltrates. Open lung biopsy revealed necrotic tissue and a sulfur granule; aerobic bacterial cultures yielded Streptomyces species. The patient was treated successfully with clarithromycin for 6 months. We review the clinical presentation and treatment of invasive streptomyces infections.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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