Journal Article

Infections Due to Sandfly Fever Virus Serotype Toscana in Spain

Joaquín Mendoza-Montero, Maria-Isabel Gámez-Rueda, José-María Navarro-Marí, Manuel de la Rosa-Fraile and Salvador Oyonarte-Gómez

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 27, issue 3, pages 434-436
Published in print September 1998 | ISSN: 1058-4838
Published online September 1998 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/514684
Infections Due to Sandfly Fever Virus Serotype Toscana in Spain

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Of the sandfly fever viruses known to be human pathogens (serotypes Toscana [TOS], Sicilian [SFS], and Naples [SFN]), only TOS has demonstrated neurotropic activity. Infections by TOS have been reported in Mediterranean countries, but the virus was previously isolated only in Italy and Portugal. We isolated 15 strains of TOS between 1988 and 1996 from the cerebrospinal fluid of patients with acute aseptic meningitis in Granada, Spain. This finding led us to study the presence of antibodies to TOS, SFS, and SFN in 1,181 adults and 87 children from different regions of Spain. We found that the prevalence of antibodies to these viruses was 26.2%, 2.2, and 11.9%, respectively; these rates imply that TOS infections are common in Spain.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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