Journal Article

Numerous Eruptive Lesions of Panniculitis Associated with Group A Streptococcus Bacteremia in an Immunocompetent Child

William Pao, Karynne O. Duncan, Jean L. Bolognia, Carolyn B. Carroll, Peter J. Hotez and Debra E. Bessen

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 27, issue 3, pages 430-433
Published in print September 1998 | ISSN: 1058-4838
Published online September 1998 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/514685
Numerous Eruptive Lesions of Panniculitis Associated with Group A Streptococcus Bacteremia in an Immunocompetent Child

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A previously healthy 13-month-old boy developed group A β-hemolytic streptococcus bacteremia coinciding with numerous eruptive subcutaneous lesions primarily on his extremities. Skin biopsy revealed infectious panniculitis; gram-positive cocci were present within both fat lobules and septa. Molecular genetic analysis of an isolate from the patient's blood revealed an emm type 4 organism displaying the emm chromosomal pattern E that is characteristic of opacity factor-producing strains; the organism also harbored the gene encoding for streptococcal pyrogenic exotoxin C (speC). To our knowledge, this clinical presentation has not yet been described in the spectrum of infections directly caused by group A β-hemolytic streptococci.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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