Journal Article

<i>Mycobacterium bovis</i> Osteomyelitis Involving a Hip Arthroplasty After Intravesicular Bacille Calmette-Guérin for Bladder Cancer

Carmen E. Guerra, Robert F. Betts, Regis J. O'Keefe and Jack W. Shilling

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 27, issue 3, pages 639-640
Published in print September 1998 | ISSN: 1058-4838
Published online September 1998 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/514714
Mycobacterium bovis Osteomyelitis Involving a Hip Arthroplasty After Intravesicular Bacille Calmette-Guérin for Bladder Cancer

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Bacille Calmette-Guérin (BCG), an attenuated strain of Mycobacterium bovis, is one of the most effective agents in the treatment of superficial bladder cancer. BCG osteomyelitis is an infrequent complication of intravesicular BCG therapy; only five cases of BCG vertebral osteomyelitis have been reported in the literature. Similarly, the infection of an indwelling extravascular device by BCG is rare; there is only one previous report documenting infection associated with an automated implantable cardiac defibrillator. We report a case of BCG osteomyelitis involving a hip arthroplasty that occurred after intravesicular administration of BCG for bladder cancer, and we review the risk factors predisposing to such infections and their treatment.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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